CRISPR Gene Editing
Bacteria have been editing their own DNA for millions of years. And now we've learned to use their trick. [1] CRISPR sequences were first discovered in the E. coli genome in 1987,
2 briefings
Bacteria have been editing their own DNA for millions of years. And now we've learned to use their trick. [1] CRISPR sequences were first discovered in the E. coli genome in 1987,
So how does it actually work? The system has two essential components: a Cas enzyme for cutting the target DNA sequence and a single guide RNA, or gRNA. [1] Think of the guide RNA